AIM: To study the effect of early rehabilitative intervention on interval QT dispersion (QTd) of acute myocardial infarction(AMI) patients without complication. METHODS: One hundred and thirteen subjects were randomly divided into the early rehabilitation therapy group (group 1, n = 54) and the control group (group 2, n = 59). Baseline data of the patients in the two groups were comparable. Patients in group 1 received early rehabilitative intervention, while patients in group 2 received traditional rehabilitation. 12-lead ECG was recorded in all subjects at the time of hospitalization (mean 9.3 +/- 1.9 hours), at the end of the first, second and third week after the onset of AMI. QTd was measured from the initial point of QRS wave to the destination of T wave, three cardiac cycles were measured with the same lead, and the average value was needed. QTd was the value that the maximal QT value subduced the minimal QT value in different leads. RESULTS: There was no significant difference in QTd between the early rehabilitation group and the control group at the time of hospitalization, at the end of one week, two weeks and three week after the onset of AMI (64 +/- 14 ms, 46 +/- 15 ms, 43 +/- 12 ms, 39 +/- 13 ms, respectively versus 67 +/- 12 ms, 48 +/- 16 ms, 41 +/- 13 ms, 40 +/- 15 ms, respectively) (t = 0.81, 0.68, 0.85, 0.38, p > 0.05). CONCLUSION: QTd is not influenced by early rehabilitative intervention on AMI patients without complication, so the electric stability of myocardium is not influenced. The early rehabilitative intervention to AMI patients without complication is safe and feasible.

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