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Evaluation of the efficacy and cost effectiveness of health education methods to increase medication adherence among adults with asthma
Windsor RA, Bailey WC, Richards JM Jr, Manzella B, Soong SJ, Brooks M
American Journal of Public Health 1990 Dec;80(12):1519-1521
clinical trial
4/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

We randomized 135 adult asthma patients to a control group, and 132 patients to an experimental group which received a special health education intervention. Four adherence measures were documented at baseline and 12-month follow-up: correct inhaler use, inhaler adherence, medication adherence, and total adherence rating. Costs to routinely deliver the intervention were $32.03/patient. Experimental group patients exhibited a significantly higher level of improvement in adherence (44%) than control group patients (2%).
Copyright by the American Public Health Association.

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