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Is forced use of the paretic upper limb beneficial? A randomized pilot study during subacute post-stroke recovery [with consumer summary]
Hammer A, Lindmark B
Clinical Rehabilitation 2009 May;23(5):424-433
clinical trial
6/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

OBJECTIVE: To evaluate the effect of two weeks of forced use of the paretic upper limb, as a supplement to the rehabilitation programme in the subacute phase after stroke, on self-rated use of that limb. DESIGN: A randomized, non-blind, parallel group, clinical, before-and-after trial. A forced use group and a conventional group were followed up one and three months after intervention. SETTING: In- and outpatient units of rehabilitation at a University Hospital. SUBJECTS: Thirty patients were allocated to two groups, 15 in each, 1 to 6 months (mean 2.4) after stroke onset. Twenty-six patients completed the study. INTERVENTIONS: The patients of both groups participated in two weeks of daily training on weekdays. In addition, the forced use group wore a restraining sling on the non-paretic arm for up to 6 hours per weekday. MAIN MEASURE: The Motor Activity Log; patients scored 0 to 5 for 30 daily tasks concerning both amount of use and quality of movement. RESULTS: The forced use group tended to achieve larger improvements immediately post-intervention, but this was not clearly demonstrated. The small differences also levelled out up to the three-month follow-up, with both groups earning an approximately 1.0 score point on both scales of the Motor Activity Log. CONCLUSIONS: This pilot study did not reveal any additional benefit of forced use on self-rated performance in daily use of the paretic upper limb. Both groups performed fairly extensive, active training with a similar duration, amount and content.

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