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Effects of exercise rehabilitation on blood pressure of patients after myocardial infarction
Kargarfard M, Rouzbehani R, Basati F
International Journal of Preventive Medicine 2010 Spring;1(2):124-130
clinical trial
5/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

OBJECTIVES: Supervised exercise cardiac rehabilitation programs have been suggested to all patients specially patients with postmyocardial infarction (MI) for many years. However, limited information is available on the usefulness of exercise rehabilitation programs in chronic MI. The aim of this study was to evaluate the outcome of supervised exercise training on MI patients by measuring both physical and physiological factors. METHODS: This was a semi-experimental randomized study. It included seventy two (35 cases, 37 controls) post-MI patients aged 40 to 67 years. They were randomly selected from those with MI based on WHO criteria who were referred to cardiac rehabilitation unit of Isfahan Shahid Chamran cardiovascular research center. After initial measurements including weight, height, functional capacity, diastolic blood pressure (DBP) and systolic blood pressure (SBP) in both resting and exercise states, patients were randomized into either the training group (n = 35) or the control group (n = 37). The training group had supervised aerobic training program, three times a week, with 60 to 70% of the maximal heart rate (HR) reserve for two months. After the training program was completed, all measurements were repeated in both groups. Data were analyzed using one-way analysis of variance (ANOVA) with repeated measures. RESULTS: Patients in exercise group showed statistically significant improvement in resting HR (81.27 +/- 7.75 bpm versus 74.17 +/- 10.11bpm, p <= 0.001), resting SBP (125.92 +/- 9.30 mmHg versus 123.54 +/- 6.82 mmHg, p <= 0.01), SBP peak (150.22 +/- 7.12 mmHg versus 133.54 +/- 6.82 mmHg, p <= 0.001), HR peak (132.51 +/- 3.06 bpm versus 142.00 +/- 3.14bpm, p <= 0.001), and exercise capacity (8.49 +/- 1.18 METs versus 9.42 +/- 1.19 METs, p <= 0.01). CONCLUSIONS: The results from the study showed that a 2-month exercise rehabilitation program in post-MI patients is useful for improving both blood pressure and exercise capacity and should be encouraged more commonly.

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