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Effect of high voltage monophasic stimulation on pressure ulcer healing: results from a randomized controlled trial [with consumer summary]
Franek A, Kostur R, Taradaj J, Blaszczak E, Szlachta Z, Dolibog P, Dolibog P, Polak A
Wounds 2011 Jan;23(1):15-23
clinical trial
6/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: Yes; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

OBJECTIVE: To investigate the effect of high voltage monophasic stimulation (HVMS) on pressure ulcer healing. METHODS: Fifty-eight patients with pressure ulcers were included and ultimately allocated into two comparative groups. Patients in group A and B were treated pharmacologically (a local bath of potassium permanganate, compresses of fibrolan, colistin, iruxol, and wet dressings containing 10% sodium chloride). Patients in group A were additionally treated with HVMS (100 nano-s, 100 Hz, 100 V) once daily, five times a week for 6 weeks. RESULTS: The relative changes in total surface area were (85.38% in group A versus 40.08% in group B); length (71.22% in group A versus 30.38% in group B); width (76.09% in group A versus 32.48% in group B); and volume (20.69% in group A versus 9.39% in group B). The Gilman Index (0.64 cm in group A versus 0.28 cm in group B) indicated a difference in favor of group A (p < 0.001). More efficient decrease of pus and greater granulation growth were observed in group A. CONCLUSION: HVMS appears to be a promising and useful treatment modality for pressure ulcers.

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