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Six-year follow-up of a randomised controlled trial examining hospital versus home-based exercise training after coronary artery bypass graft surgery
Smith KM, McKelvie RS, Thorpe KE, Arthur HM
Heart 2011 Jul;97(14):1169-1174
clinical trial
5/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

OBJECTIVE: To compare the long-term effectiveness of hospital versus telephone-monitored home-based exercise training during cardiac rehabilitation (CR) on exercise capacity and habitual physical activity. DESIGN: Six-year follow-up of patients who participated in a randomised controlled trial of hospital versus monitored home-based exercise training during CR after coronary artery bypass graft surgery. Setting Outpatient CR centre in Central-South Ontario, Canada. PARTICIPANTS: 196 patients who participated in the original randomised controlled trial and who attended an evaluation 1 year after CR. INTERVENTIONS: 6 months of home or hospital-based exercise training during CR. MAIN OUTCOME MEASURES: Peak oxygen uptake (peakVO2), Physical Activity Scale in the Elderly (PASE) to assess habitual activity, semi-structured interviews to assess vital status, demographic and descriptive information. RESULTS: Of the 196 eligible patients, 144 (75.5%; 74 Hospital, 70 Home) were available for participation. Patients were predominantly male (n = 120; 83.3%) aged 70 +/- 9.5 years. Clinical and sociodemographic outcomes were similar in both groups. While exercise performance declined over time, there were significant between-group differences in peakVO2 (1,506 +/- 418 ml/min versus 1,393 +/- 341 ml/min; p = 0.017) and PASE scores (166.7 +/- 90.2 versus 139.7 +/- 66.5; p = 0.001) at 6-year follow-up in favour of the home group. CONCLUSIONS: Home and hospital-based exercise training maintained exercise capacity above pre-CR levels 6 years after CR. Exercise training initiated in the home environment in low-risk patients undergoing coronary artery bypass graft surgery conferred greater long-term benefit on VO2 and persistent physical activity compared with traditional hospital-based CR.
Reproduced with permission from the BMJ Publishing Group.

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