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Weight loss in obese patients with type 2 diabetes: effects of telemonitoring plus a diet combination -- the active body control (ABC) program |
Luley C, Blaik A, Reschke K, Klose S, Westphal S |
Diabetes Research and Clinical Practice 2011 Mar;91(3):286-292 |
clinical trial |
5/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
AIMS: We evaluate the efficacy of the "active body control (ABC) program" for weight reduction in patients with type 2 diabetes. METHODS: The ABC program combines telemonitoring of the physical activity with a low-calorie diet also preferring carbohydrates with low glycemic indexes. In this 6-month, randomized, clinical trial 35 patients (aged 57 +/- 9 years; BMI 35.3 +/- 5.7 kg/m2) were treated according to the ABC program and 35 control patients (aged 58 +/- 7 years; BMI 34.8 +/- 5.9 kg/m2) received standard therapy. RESULTS: After 6 months the mean weight loss in the intervention group was 11.8 kg +/- 8.0 kg. Glucose and HbA1c were lowered by respectively 1.0 mmol/l and 0.8 percentage points (p = 0.000, respectively). The proportion of patients with HbA1c > 7% fell from 57% to 26%. Antidiabetic drugs were discontinued in 13 patients (39%) and reduced in 14 (42%). The reduction of costs on medication per patient was 83 in 6 months. In the control group, there were no relevant changes in body weight, laboratory values or drug treatment. CONCLUSIONS: The ABC program effectively lowers body weight, Hb1Ac and antidiabetic drug use in patients with type 2 diabetes.
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