This study compared the effects of resistance exercise (RE) intensities on blood glucose (GLUC) of individuals without (ND) and with type-2 diabetes (T2D). Nine individuals with T2D and 10 ND performed: (a) RE circuit at 23% of 1 maximal repetition (1RM) (RE_L); (b) RE circuit at 43% 1RM (RE_M); and (c) control (CON) session. Blood lactate (LAC) and GLUC were measured before, during, and postinterventions. Double product (DP) and rate of perceived exertion (RPE) were recorded. The area under the curve (AUC) revealed the effects of RE circuits in reducing GLUC in individuals with T2D (RE_L 12,556 +/- 3,269 versus RE_M 13,433 +/- 3,054 versus CON 14,576 +/- 3,922 mg/dl-145minutes; p < 0.05) with a lower AUC of GLUC in RE_L in comparison to RE_M. Similarly, for ND the RE_L reduced the AUC of GLUC when compared with RE_M and CON (RE_L 10,943 +/- 956 versus RE_M 12,156 +/- 1,062 versus CON 11,498 +/- 882 mg/dl-145minutes; p < 0.05). The AUC of GLUC was higher for T2D compared with ND on CON condition (p = 0.02). However, after RE circuits the difference between groups for AUC of GLUC was abolished. The RE_M for T2D was more stressful when compared with RE_L for LAC (CON 1.3 +/- 0.5 versus RE_L 5.5 +/- 1.5 versus RE_M 6.8 +/- 1.3 mmol/L; p < 0.05), DP (CON 8,415 +/- 1,223 versus RE_L 15,980 +/- 2,007 versus RE_M 18,047 +/- 3,693 mmHg/bpm; p < 0.05), and RPE (RE_L 11 +/- 2 versus RE_M 13 +/- 2 Borg Scale; p < 0.05). We concluded that RE_L and RE_M were effective in reducing GLUC for individuals with T2D, with lower cardiovascular-metabolic and perceptual stress being observed for RE_L. These data suggest that acute RE sessions at light or moderate intensities are effective for controlling GLUC in individuals with T2D.

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