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| (Clinical research of organised stroke care model with integrated Chinese traditional and western medicine in primary hospital) [Chinese - simplified characters] |
| Pei Z, Zhu J, He R, Peng Z, Yang A, Zhang X, Chen X, Yu G |
| Zhongguo Xiandai Shenjing Jibing Zazhi [Chinese Journal of Contemporary Neurology and Neurosurgery] 2011 Apr;11(2):221-225 |
| clinical trial |
| 5/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
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OBJECTIVE: To investigate the clinical effect of the organized stroke care model assisted with Chinese traditional medicine and acupuncture treatment for recovery in primary hospital. METHODS: Two hundred and thirty-six stroke patients were randomly divided into organized care group (organized group, n = 121) and the traditional care group (control group, n = 115). The short-term clinical curative effect, case-fatality rates, and complication incidence of the 2 groups were compared by National Institute of Health Stroke Scale (NIHSS), Barthel Index (BI) and Oxford Handicap Score(OHS). RESULTS: Before treatment, NIHSS score was (20.15 +/- 3.45) in organized group and (19.85 +/- 4.86) in control group, the difference was not statistically significant (p > 0.05). During treatment, NIHSS score, BI and OHS score was 11.28 +/- 4.25, 78.00 +/- 22.50 and 1.85 +/- 1.40 respectively in organized group, and was 16.40 +/- 3.80, 62.00 +/- 23.60 and 2.60 +/- 1.25 respectively in control group, at 21 d. The differences were all statistically significant (p = 0.000, for all). At 90 d, NIHSS score, BI and OHS score was 4.76 +/- 3.16, 84.00 +/- 20.12 and 1.30 +/- 0.98 respectively in organized group, and was 12.23 +/- 4.35, 70.00 +/- 22.30 and 2.10 +/- 1.40 respectively in control group, all differences were also statistically significant (p = 0.000, for all). The total curative effect at 21 d (80.99%, 98/121) and 90 d (88.43%, 107/121) in organized group were all higher than that in control group (61.74%, 71/115 and 72.17%, 83/115; 21 d z = 6.207, p = 0.013; 90 d z = 8.302, p = 0.004). The complication incidence in organized group (30.58%, 37/121) was significantly lower than that in control group (69.57%, 80/115; Chi2 = 35.851, p = 0.000). CONCLUSION: In primary hospital, the curative effect of organized stroke care assisted with Chinese traditional medicine and acupuncture is better than traditional treatment for stroke.
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