OBJECTIVE: To compare the effectiveness of two procedures increasing the Botulinum toxin type A effect for wrist and finger flexor spasticity after stroke. DESIGN: A single-blind randomized trial. SUBJECTS: Seventy patients with upper limb post-stroke spasticity. METHODS: Adults with wrist and finger flexor muscles spasticity after stroke were submitted to Botulinum toxin type A therapy. After the treatment, the subjects injected were randomly divided into two groups and submitted to adhesive taping (group A) or daily muscle manual stretching, passive articular mobilization of wrist and fingers, and palmar splint (group B) for 10 days. We measured spasticity with Modified Ashworth Scale, related disability with Disability Assessment Scale, and fingers position at rest. The measurements were done at baseline, after two weeks, and after one month from the treatment session. RESULTS: After two weeks, subjects in group A reported a significantly greater decrease in spasticity scores (Modified Ashworth Scale fingers mean (standard deviation) 1.3+/- 0.6 versus 2.1+/- 0.6; Modified Ashworth Scale wrist 1.7 +/- 0.6 versus 2.3 +/- 0.8), and after one month in spasticity and disability scores (Modified Ashworth Scale fingers mean (standard deviation) 1.9 +/- 0.7 versus 2.5 +/- 0.6; Modified Ashworth Scale wrist 2.0 +/- 0.7 versus 2.6 +/- 0.6; Disability Assessment Scale 1.6 +/- 0.7 versus 2.1 +/- 0.7) compared with group B subjects. Subjects in group A reported also a significantly improved fingers position at rest compared with group B subjects after two weeks (2.8 +/- 0.9 versus 2.1 +/- 0.7) and one month (2.3 +/- 0.7 versus 1.5 +/- 0.6). CONCLUSIONS: Adhesive taping of wrist and finger flexor muscles appeared to enhance the effect of Botulinum toxin type A therapy more than daily manual muscle stretching combined with passive articular mobilization and palmar splint.

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