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Combined aerobic and resistance exercise improves glycemic control and fitness in type 2 diabetes
Maiorana A, O'Driscoll G, Goodman C, Taylor R, Green D
Diabetes Research and Clinical Practice 2002 May;56(2):115-123
clinical trial
6/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

We investigated the effect of an 8 week circuit training (CT) program, combining aerobic and resistance exercise, on indices of glycemic control, cardiorespiratory fitness, muscular strength and body composition in 16 subjects (age 52 +/- 2 years) with type 2 diabetes using a prospective randomised crossover protocol. Submaximal exercise heart rate and rate pressure product were significantly lower after training (p < 0.05), whilst ventilatory threshold increased (11.8 +/- 0.7 versus 13.8 +/- 0.6 ml/kg/min, p < 0.001). Muscular strength also increased with training (403 +/- 30 to 456 +/- 31 kg, p < 0.001), whilst skinfolds (148.7 +/- 11.5 versus 141.1 +/- 10.7 mm, p < 0.05), % body fat (29.5 +/- 1.0 versus 28.7 +/- 1.1%, p < 0.05) and waist:hip ratio (99.2 +/- 1.5 versus 97.9 +/- 1.4%, p < 0.05) significantly decreased. Concurrently, peak oxygen uptake (p < 0.05) and exercise test duration (p < 0.001) increased following training, whilst glycated hemoglobin (p < 0.05) and fasting blood glucose (p < 0.05) decreased. CT is an effective method of training that improved functional capacity, lean body mass, strength and glycemic control in subjects with type 2 diabetes.
With permission from Excerpta Medica Inc.

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