This study aimed to determine the effects of physical exercise based rehabilitation programs on quality of life of patients with Parkinson's disease through an systematic review of randomized clinical trials. For this purpose the following electronic databases were selected: Medline by PubMed, Cochrane, Web of Science and PEDro. The search strategy included the proposed descriptors in the Medical Subject Headings (MeSH), associated with a sensitive list of terms to search for randomized controlled trials (RCTs), without year and language restrictions. Fourteen studies were potentially relevant, and these studies were included. It can be concluded that physical exercise based rehabilitation programs realized 2 to 4 times a week, 60 minutes each session, for 6 to 12 weeks, and follow-up of 3 months promotes significant positive effects on quality of life in Parkinson's disease patients at mild to moderate stages and disease duration around six years.

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