OBJECTIVE: To investigate the effectiveness of a physical activity intervention for use within a comprehensive outpatient rehabilitation program for individuals with brain injury. DESIGN: Quasi-experimental comparison group design with 3-month follow-up. SETTING: Comprehensive outpatient rehabilitation clinic which is a transitional setting between acute inpatient rehabilitation and community dwelling. PARTICIPANTS: 47 individuals with a brain injury were enrolled into either the intervention (n = 22, 8 female, 14 male; mean age 48.68) or control group (n = 25, 9 female, 16 male; mean age 46.23). INTERVENTION: Consisted of an 8-week informational and social/behavioral program that focused on enabling individuals to become independently active. The control group completed the standard of care typically available to patients in comprehensive outpatient rehabilitation. MAIN OUTCOME MEASURES: Behavioral Risk Factor Surveillance Survey self-report physical activity items, Exercise Self-Efficacy Scale, Mayo Portland Adaptability Inventory-4. RESULTS: The intervention group reported significantly (p < 0.001) greater weekly activity, self-efficacy, and rehabilitation outcomes at the completion of the program as well as at the three-month follow-up when compared to the control group. Significantly, individuals in the experimental group reported increasing their weekly activity from 45 minutes pre-program to 72 minutes post- program (d = 2.12; CI 1.78 to 2.52), and 67 minutes at 3-month follow-up. CONCLUSIONS: Findings suggest that the intervention may be effective in increasing the physical activity behaviors of individuals engaged in comprehensive outpatient post-brain injury.

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