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Evaluacion de un programa de ejercicio fisico supervisado en pacientes sedentarios mayores de 65 anos con diabetes mellitus tipo 2 (Evaluation of a supervised physical exercise program in sedentary patients over 65 years with type 2 diabetes mellitus) [Spanish; with consumer summary]
Parra-Sanchez J, Moreno-Jimenez M, Nicola CM, Nocua-Rodriguez II, Ameglo-Parejo MR, del Carmen-Pena M, Cordero-Prieto C, Gajardo-Barrena MJ
Atencion Primaria 2015 Nov;47(9):555-562
clinical trial
6/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

OBJECTIVE: To analyze whether an exercise program can modify glycated hemoglobin (HbA1c), blood pressure (BP), body mass index (BMI), lipids, cardiovascular risk profile (CVR), self-perceived health status (SHS), and pharmaceutical expenditure (PE). DESIGN: A randomized, single blind, controlled trial. INTERVENTION: Program of supervised aerobic physical exercise. Analysis by intention to treat. LOCATION: Primary care: 2 rural health areas, Health Area of Navalmoral, Caceres, Extremadura, Spain. PARTICIPANTS: 100 type 2 diabetic patients, aged 65 to 80 years, sedentary. Distribution: 50% control group (CG) and 50% intervention group (IG). Abandoned 12%. INTERVENTION: Monitored aerobic exercise: 40minutes, 2 days/week, 3 months. KEY MEASURES: HbA1c, BP, BMI, lipid, CVR, SHS, PE. Complications during exercise. RESULTS: There were post-intervention differences between groups in HbA1c, BP, BMI, cholesterol and SHS. In the IG, there was a significant decrease in HbA1c 0.2 +/- 0.4% (95% CI 0.1 to 0.3), systolic BP 11.8 +/- 8.5mmHg (95% CI 5.1 to 11.9), BMI 0.5 +/- 1 (95% CI 0.2 to 0.8), total cholesterol 14 +/- 28.2mg/dl (95% CI 5.9 to 22.2), LDL 18.3 +/- 28.2mg/dl 95% CI 10.2 to 26.3), CVR 6.7 +/- 7.7% (95% CI 4.5 to 8.9), PE 3.9 +/- 10.2 (95% CI 0.9 to 6.8), and an increase in SHS 4.7 +/- 5.7 (95% CI 3 to 6.3). CONCLUSIONS: In diabetics over 65 years, a program of monitored aerobic exercise, of easy implementation, improves HbA1c, BP, cholesterol, CVR, PE, and SHS.

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