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Low-volume high-intensity interval training as a therapy for type 2 diabetes |
Alvarez C, Ramirez-Campillo R, Martinez-Salazar C, Mancilla R, Flores-Opazo M, Cano-Montoya J, Ciolac EG |
International Journal of Sports Medicine 2016 Aug;37(9):723-729 |
clinical trial |
6/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
Our purpose was to investigate the effects of low-volume, high-intensity interval training (HIT) on cardiometabolic risk and exercise capacity in women with type 2 diabetes mellitus (T2DM). Sedentary overweight/obese T2DM women (age 44.5 +/- 1.8 years; BMI 30.5 +/- 0.6 kg/m2) were randomly assigned to a tri-weekly running-based HIT program (n = 13) or non-exercise control follow-up (CON; n = 10). Glycemic control, lipid and blood pressure levels, endurance performance, and anthropometry were measured before and after the follow-up (16 weeks) in both groups. Medication intake was also assessed throughout the follow-up. Improvements (p < 0.05) on fasting glucose (14.3 +/- 1.4%), HbA1c (12.8 +/- 1.1%), systolic blood pressure (3.7 +/- 0.5 mmHg), HDL-cholesterol (21.1 +/- 2.8%), triglycerides (17.7 +/- 2.8%), endurance performance (9.8 +/- 1.0%), body weight (2.2 +/- 0.3%), BMI (2.1 +/- 0.3%), waist circumference (4.0 +/- 0.5%) and subcutaneous fat (18.6 +/- 1.4%) were found after HIT intervention. Patients of HIT group also showed reductions in daily dosage of antihyperglycemic and antihypertensive medication during follow-up. No changes were found in any variable of CON group. The HIT-induced improvements occurred with a weekly time commitment 56 to 25% lower than the minimal recommended in current guidelines. These findings suggest that low-volume HIT may be a time-efficient intervention to treat T2DM women.
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