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Time course of exercise training-induced muscle strength changes in type 2 diabetes |
Mathis RA, Taylor JD, Fletcher JP, Rainey J, Cade WT, Bandy WD |
Cardiopulmonary Physical Therapy Journal 2016 Oct;27(4):133-139 |
clinical trial |
6/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: Yes; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
To investigate longitudinal muscle strength changes in response to exercise training in people with type 2 diabetes. METHODS: Twenty-one people with type 2 diabetes were randomly allocated to either a moderate or high-intensity exercise training group with the only difference between the groups being the prescribed exercise training intensity. Muscle strength (8 repetition maximum in kilograms) was measured weekly for 12 weeks using the chest press, leg press, row, and knee extension exercises. Muscle strength was expressed as the sum of 8 repetition maximum scores for each exercise. RESULTS: Linear mixed models indicated significant gains inmuscle strength (p < 0.001) in both groups and no significant difference in gains in muscle strength (p = 0.47) between the groups. Pooled data from both groups indicated significant improvement inmuscle strength (p < 0.05) week-to-week beginning afterweek 1 and continued untilweek 9. CONCLUSION: Participation in either a moderate or high-intensity exercise training program can result in similar gains in muscle strength for people with type 2 diabetes. Muscle strength improvements can occur on a weekly basis for the first 8 weeks of exercise training, with a plateau in gains occurring at week 9 through week 12.
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