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Evaluating pulmonary function, aerobic capacity, and pediatric quality of life following a 10-week aerobic exercise training in school-aged asthmatics: a randomized controlled trial
Abdelbasset WK, Alsubaie SF, Tantawy SA, Abo Elyazed TI, Kamel DM
Patient Preference & Adherence 2018 Jun 15;12:1015-1023
clinical trial
7/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: Yes; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

BACKGROUND: It has been documented that aerobic exercise may increase pulmonary functions and aerobic capacity, but limited data has evaluated a child's satisfaction and pediatric quality of life (PQoL) with exercise training. OBJECTIVES: This study aimed to investigate the effects of moderate-intensity exercise training on asthmatic school-aged children. SUBJECTS AND METHODS: This study included 38 school-aged children with asthma (23 males and 15 females) aged between 8 to 12 years. They were randomly assigned to two groups, aerobic exercise (AE) and conventional treatment (Con TTT) groups. The AE group received a program of moderate-intensity aerobic exercise for 10 weeks with asthma medications and the Con TTT group received only asthma medications without exercise intervention. A home respiratory exercise was recommended for the two groups. Aerobic capacity was investigated using maximal oxygen uptake (VO2max), 6-minute walk test (6MWT), and fatigue index. PQoL was evaluated using Pediatric Quality of Life Questionnaire (PQoLQ). Also, pulmonary function tests were performed, and the results recorded. RESULTS: The findings of this study showed significant improvements in pulmonary functions and VO2max in the two groups; however, this improvement was significantly higher in the AE group than in the Con TTT group (p < 0.05). The 6MWT and fatigue index improved in the AE group (p < 0.05) but not in the Con TTT group (p > 0.05). All dimensions of PQoL significantly improved in the AE group (p < 0.05), but there was no significant improvement in the Con TTT group after the 10-week intervention period (p > 0.05). CONCLUSION: Ten weeks of physical exercise had beneficial effects on pulmonary functions, aerobic capacity, and PQoL in school-aged children with asthma. Effort and awareness should be dedicated to encouraging the active lifestyle among different populations, especially asthmatic children.

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