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Effects of Tai Chi on cerebral haemodynamics and health-related outcomes in older community adults at risk of ischaemic stroke: a randomized controlled trial
Zheng G, Zheng X, Li J, Duan T, Ling K, Tao J, Chen L
Journal of Aging and Physical Activity 2019 Feb 12:Epub ahead of print
clinical trial
6/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: No; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

This study investigated the effects of Tai Chi compared to no exercise control on the cerebral haemodynamic parameters and other health-related factors in community older adults at risk of ischemic stroke. 170 eligible participants were randomly allocated to Tai Chi or control group. The cerebral haemodynamic parameters and physical fitness risk factors of cardiovascular disease were measured at baseline, 12 weeks and 24 weeks. After 12-weeks intervention, Tai Chi significantly improved the minimum of blood flow velocity (BFVmin), BFVmean, pulsatility index and resistance index of the right anterior cerebral artery, and BFVmax, BFVmin and BFVmean parameters of the right middle cerebral artery. Tai Chi training also decreased triglyceride, fasting blood glucose and homocysteine levels, and improved balance ability. Therefore, the supervised 12-week Tai Chi exercise had potential beneficial effects on cerebral haemodynamics, plasma risk factors and balance ability in older community adults at risk of ischaemic stroke.

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