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Additional early active repetitive motor training did not prevent contracture in adults receiving task-specific upper limb training after stroke: a randomised trial [with consumer summary]
Horsley S, Lannin NA, Hayward KS, Herbert RD
Journal of Physiotherapy 2019 Apr;65(2):88-94
clinical trial
8/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: Yes; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: Yes; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

QUESTION: In adults undergoing rehabilitation after stroke, does 1 hour of additional active repetitive reaching per day prevent or reduce upper limb contracture? DESIGN: Multi-centre, randomised controlled trial with concealed allocation, assessor blinding, and intention-to-treat analysis. PARTICIPANTS: Fifty adults undergoing rehabilitation after stroke who were unable to actively extend the affected wrist past neutral or were unable to flex the affected shoulder to 90 deg. SETTING: Three inpatient rehabilitation units in Australia. INTERVENTION: Both groups received usual upper limb therapy 5 days a week for 5 weeks. In addition, the experimental group received up to 1 hour a day of active, intensive, repetitive upper limb training using the SMART Arm device 5 days a week for 5 weeks. OUTCOME MEASURES: Measures were collected at baseline (week 0), after intervention (week 5) and at follow-up (week 7). The primary outcomes were passive range of wrist extension, elbow extension, and shoulder flexion at week 5. The secondary outcomes were: the three primary outcomes measured at week 7; passive range of shoulder external rotation; arm function; and pain at rest, on movement and during sleep measured at weeks 5 and 7. RESULTS: Following an average of 2310 reaching repetitions, the mean effect at week 5 on passive range of wrist extension was 1 deg (95% CI -6 to 8), elbow extension -6 deg (95% CI -12 to -1), and shoulder flexion 5 deg (95% CI -8 to 17). There were no statistically significant or clinically important effects of the intervention on any secondary outcomes. CONCLUSION: In adults who are already receiving task-specific motor training for upper limb rehabilitation following stroke, 5 weeks of up to 1 hour of additional daily active repetitive motor training using the SMART Arm device did not prevent or reduce contracture in upper limb muscles. TRIAL REGISTRATION: ACTRN12614001162606.

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