BACKGROUND: Kinesiotaping (KT), has emerged as an interesting and relatively novel method for treating musculoskeletal conditions. To date, none of the systematic reviews with meta-analysis have addressed the efficacy of KT alone (without any other intervention) over sham taping (ST). OBJECTIVE: The present meta-analysis aimed to investigate the effectiveness of KT versus ST in patients with musculoskeletal conditions in interventions lasting at least 1 week on musculoskeletal conditions and functional performance outcomes. DATA SOURCE: Manual and electronic searches (CENTRAL, Embase, Medline and PEDro) were conducted using Kinesiotaping, strapping, musculoskeletal pain and musculoskeletal conditions. STUDY SELECTION CRITERIA: Randomised controlled trials on adults with a diagnosis of musculoskeletal conditions. DATA EXTRACTION AND DATA SYNTHESIS: Two researchers independently carried out the search and the third author was referred to for arbitration. The methodological quality of the studies using the PEDro scale and GRADE approach. RESULTS: Six RCTs were identified and included in the meta-analysis. When compared with ST in adults with chronic non-specific low-back pain (LBP), KT resulted in superior effects on pain at follow-up, but the pooled pain in the immediate post-treatment period and disability scores (in the immediate post-treatment period and at follow-up) were not significantly different. Generally, all results were supported by low quality evidence according to GRADE criteria. CONCLUSION: Our findings indicate inconclusive and low-quality evidence of a beneficial effect of KT alone over ST in LBP and knee osteoarthritis. SYSTEMATIC REVIEW REGISTRATION NUMBER: PROSPERO CRD42018084151.

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