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Clinical efficacy of a medical centre- and home-based cardiac rehabilitation program for patients with coronary heart disease after coronary bypass graft surgery |
Aronov D, Bubnova M, Iosseliani D, Orekhov A |
Archives of Medical Research 2019 Apr;50(3):122-132 |
clinical trial |
4/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
BACKGROUND: Rehabilitation measures are crucial for maintaining clinical benefits of coronary artery bypass grafting (CABG) surgery. We evaluated the clinical efficacy of a medical centre- and home-based cardiac rehabilitation (CR) for patients after CABG in an out-patient setting. METHODS: The study included 36 male patients 3 to 8 weeks after CABG that were randomly assigned to either study or control group. Patients from the study group performed a 60 min exercise in controlled setting 3 times a week for 4 months followed by home-based exercise later on, while patients from the control group only received a recommendation to perform the exercise at home in an uncontrolled setting. Total duration of the follow-up was 12 months. RESULTS: Physical endurance in the study group increased by 32.6% (p < 0.05) in comparison to baseline after 4 months, and was maintained at this level after 12 months, while in the control group, an improvement of 9.8% (p < 0.05) was observed after 12 months. Moreover, patients from the study group demonstrated a stable level of such risk factors as blood total and low-density lipoprotein cholesterol, while in the control group, these parameters increased by 10.2% (p < 0.05) and 15.6% (p < 0.05) respectively by the end of follow-up. Controlled medical centre-based exercise resulted in improvement of patients' quality of life and reduction of cardiovascular complications (11.1% against 39.2% in the control group). CONCLUSION: The integral (medical centre and home-based) stage III CR program after CABG helped reducing cardiovascular risk factors, and improved clinical parameters and functional capacity of patients.
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