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A behavioral intervention can decrease asthma exacerbations in older adults
Baptist AP, Hao W, Song PX, Carpenter L, Steinberg J, Cardozo LJ
Annals of Allergy, Asthma, & Immunology 2020 Mar;124(3):248-253
clinical trial
5/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: No; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: No. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

BACKGROUND: Older adults have higher rates of asthma morbidity and mortality compared with younger age groups. Few interventions are tailored to this population. OBJECTIVE: To evaluate a self-management asthma intervention in older adults. METHODS: Adults age 55 and older with persistent asthma were enrolled into blinded, randomized controlled trial of a 6-session asthma self-management intervention. This educational intervention was conducted in group sessions and through individual telephone calls. Outcomes including asthma exacerbations (defined as unscheduled office visits, emergency department visits, or hospitalizations for asthma), spirometric values, FeNO, asthma control, asthma quality of life, and asthma self-management were assessed at 3, 6, and 12 months. RESULTS: One hundred eighty-nine subjects were enrolled, 172 were randomized and received at least 1 treatment dose, and 145 (84%) were analyzed at 12 months. On a modified intent-to-treat analysis, those in the intervention group were less likely to have an asthma exacerbation (26.9% versus 47.1%, p = 0.01), had a lower asthma exacerbation rate (0.8 versus 1.9, p = 0.02), had better asthma control (19.9 versus 18.6, p = 0.08), and had a higher asthma self-management score (8.9 versus 8.4, p = 0.03). After a mixed-model analysis to control for confounding factors, a decrease in asthma exacerbations (p = 0.02), as well as a decreased asthma exacerbation rate (p = 0.04), remained statistically significant, whereas asthma control and self-management did not. No other significant outcome differences were found. CONCLUSION: A 6-session asthma self-management intervention can successfully decrease asthma exacerbations among older adults.

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