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The effect of an active video game intervention on physical activity, motor performance, and fatigue in children with cancer: a randomized controlled trial
Hamari L, Jarvela LS, Lahteenmaki PM, Arola M, Axelin A, Vahlberg T, Salantera S
BMC Research Notes 2019 Nov 29;12(784):Epub
clinical trial
5/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

OBJECTIVE: To evaluate the effect of active video games in promoting physical activity and motor performance, and reducing fatigue in children with cancer. A randomized controlled trial was conducted. The intervention included playing Nintendo Wii Fit (Nintendo Co, Ltd, Kyoto, Japan) for 30 min/day for 8 weeks. Physical activity was estimated with accelerometers, physical activity diaries and questionnaires. Movement-ABC2 and PedsQL were used to examine motor performance and fatigue. Intervention experiences and fidelity were examined with an interview. RESULTS: Participants (n = 36 children with cancer, 3 to 16 years-old) were randomly assigned to the intervention and control groups. The median (min-max) accelerometer counts/h (500 (131 to 1,130) versus 385 (116 to 1,012), p = 0.63) and physical activity min/day (34 (0 to 150) versus 23 (0 to 260), p = 0.95) did not differ between the groups. Change between the pre-test and post-test regarding motor performance and fatigue was similar in both groups (motor performance p = 0.77; fatigue p = 1.00). Participants experienced playing active video games meaningful, but the intervention was not followed completely as instructed. Overall, the physical activity levels were low and one fourth of the children had or were at risk of having movement difficulties. TRIAL REGISTRATION: identifier NCT01748058 (October 15, 2012).

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