OBJECTIVE: To evaluate the efficacy of a newly developed evidence-based low back pain (LBP) management smartphone application. DESIGN: A double-blinded randomized controlled trial where participants randomly assigned to either an experimental group (EG) or a control group (CG). SETTING: Governmental and private institutions. PARTICIPANTS: About 40 office workers, aged 30 to 55 years, had pain due to non-specific LBP > 3 on visual analogue scale, and with pain chronicity > 3 months. INTERVENTIONS: The EG received full version of the application 'Relieve my back' included evidence-based instructions and therapeutic exercises for LBP management, whereas the CG received placebo version included instructions about nutrition. MAIN MEASURES: Primary outcome measures included pain measured by visual analogue scale (VAS), disability measured by Oswestry Disability Index (ODI), and quality of life measured by Short-Form Health Survey (SF-12). RESULTS: Following six weeks of using the application, compared to CG, the EG group demonstrated significant decrease in pain intensity (-3.45 (2.21) versus -0.11 (1.66), p < 0.001), in ODI score (-11.05 (10.40) versus -0.58 (9.0), p = 0.002), and significant increase in physical component of SF-12 (12.85 (17.20) versus -4.63 (12.04), p = 0.001). CONCLUSION: 'Relieve my back' application might be efficacious in reducing pain and disability and improving the quality of life of office workers with non-specific LBP.

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