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High-intensity arm resistance training does not lead to better outcomes than low-intensity resistance training in patients after subacute stroke: a randomized controlled trial [with consumer summary] |
Hogg S, Holzgraefe M, Druge C, Hauschild F, Herrmann C, Obermann M, Mehrholz J |
Journal of Rehabilitation Medicine 2020 Jun;52(6):jrm00067 |
clinical trial |
8/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: Yes; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: Yes; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
OBJECTIVE: To describe the effects of 2 levels of intensity of arm resistance training on grip strength, arm function, activities, participation, and adverse events in patients with subacute stroke. DESIGN: A randomized controlled and preregistered trial with concealed allocation, assessor blinding and intention-to-treat analysis. PATIENTS: Patients with subacute stroke and upper extremity hemiparesis. METHODS: After randomization the experimental group received a 3-week high-intensity arm resistance training (HIT). The control group completed a 3-week low-intensity arm resistance training (LIT). The primary outcome was grip strength. Secondary outcomes included the Motricity Index, Fugl-Meyer Assessment for the upper limb, Box and Block Test, Goal Attainment Scale, Modified Ashworth Scale, and adverse events. All outcomes were assessed at baseline and after 3 weeks of intervention. RESULTS: A total of 43 patients were investigated (HIT, n = 23; LIT, n = 20). All primary and secondary outcomes improved after the 3-week training, but no significant between-group differences were found. Adverse events occurred in 5% of training sessions (19/369). CONCLUSION: The results of this study did not show differential effects on any outcome of 2 forms of arm resistance training in patients with subacute stroke.
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