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The effects of cardiac exercise rehabilitation training on the cardiopulmonary function and quality of life in patients with chronic stable heart failure |
Yu J, Wang M, Fang J, Lin Z |
International Journal of Clinical and Experimental Medicine 2020;13(8):5983-5990 |
clinical trial |
5/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
OBJECTIVE: To explore the effects of cardiac exercise rehabilitation training on the cardiopulmonary function and quality of life in patients with chronic stable heart failure. METHOD(S): A prospective study was conducted on 84 patients with chronic stable heart failure who were admitted to the department of cardiology in our hospital from September 2018 to September 2019. They were randomly assigned to a control group and an observation group. The patients in the control group received conventional drug treatment, and the patients in the observation group received cardiac exercise rehabilitation training in addition to the conventional drug treatment. The cardiopulmonary exercise test (CPET) and 6-minute walking distance test results were recorded and compared between the two groups before and after the treatment. The patients' N-terminal pro-brain natriuretic peptide (NT pro-BNP) plasma levels were measured in the laboratory. Their quality of life was evaluated using the MOS item short from health survey (SF-36) rating scale. RESULT(S): After the treatment, the peak heart rate, ventilation/carbon dioxide slope (VE/VCO2slop), and NT pro-BNP levels of the two groups were all largely decreased compared to the levels before the treatment, and there were significant differences between the two groups (p < 0.05). In addition, the patients' exercise tolerance (METs), volume peak oxygen (VO2peak) levels, SF-36 scores, 6-min walking distances, pulse oxygen levels, and anaerobic thresholds were all elevated through the treatment, and significant differences still existed between the two groups (p < 0.05). CONCLUSION(S): Cardiac exercise rehabilitation training can improve the cardiopulmonary function and enhance both the exercise endurance and quality of life of patients with chronic stable heart failure to a certain extent.
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