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Effectiveness of specific stabilization exercise compared with traditional trunk exercise in women with non-specific low back pain: a pilot randomized controlled trial
Minobes-Molina E, Rosa Nogues M, Giralt M, Casajuana C, de Souza DLB, Jerez-Roig J, Romeu M
PeerJ 2020 Nov 27;8:e10304
clinical trial
5/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

BACKGROUND: Non-specific low back pain (LBP) is the leading cause of disability worldwide. The primary physiotherapeutic treatment for LBP is physical exercise, but evidence suggesting a specific exercise as most appropriate for any given case is limited. OBJECTIVE: To determine if specific stabilization exercise (SSE) is more effective than traditional trunk exercise (TTE) in reducing levels of pain, disability and inflammation in women with non-specific low back pain (LBP). DESIGN: A pilot randomized controlled trial was conducted in Rovira i Virgili University, Catalonia. METHODS: Thirty-nine females experiencing non-specific LBP were included in two groups: the TTE program and SSE program, both were conducted by a physiotherapist during twenty sessions. The primary outcome was pain intensity (10-cm visual analogue scale). Secondary outcomes were disability (Roland Morris Disability Questionnaire), and inflammation (IL-6 and TNF-alpha plasma levels). Measurements were taken at baseline, at half intervention, at post-intervention, and a month later. RESULTS: Mean group differences in change from baseline to post-intervention for TTE were: -4.5 points (CI 3.3 to 5.6) for pain, -5.1 points (CI 3.0 to 7.3) for disability, 0.19 pg/mL (95% CI -1.6 to 1.2) for IL-6 levels, and 46.2 pg/mL (CI 13.0 to 85.3) for TNF-alpha levels. For SSE, differences were: -4.3 points (CI 3.1 to 5.6) for pain, -6.1 points (CI 3.7 to 8.6) for disability, 1.1 pg/mL (CI 0.0 to 2.1) for IL-6 levels, and 12.8 pg/mL (95% CI -42.3 to 16.7) for TNF-alpha levels. There were an insignificant effect size and no statistically significant overall mean differences between both groups. CONCLUSION: This study suggests that both interventions (traditional trunk and specific stabilization exercises) are effective in reducing pain and disability in non-specific LBP patients, but the two programs produce different degrees of inflammation change. CLINICAL TRIAL REGISTRATION NUMBER: NCT02103036.

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