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Liuzijue Qigong versus traditional breathing training for patients with post-stroke dysarthria complicated by abnormal respiratory control: results of a single-center randomized controlled trial [with consumer summary]
Wang J, Li G, Ding S, Yu L, Wang Y, Qiao L, Wu Q, Ni W, Fan H, Zheng Q, Zhang Y, Li H
Clinical Rehabilitation 2021 Jul;35(7):999-1010
clinical trial
8/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: Yes; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: Yes; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

OBJECTIVE: The aim of the study was to investigate whether Liuzijue Qigong could improve the ability of respiratory control and comprehensive speech in patients with stroke dysarthria. DESIGN: A randomized controlled trial. SETTING: The research was carried out in the department of rehabilitation. Participants: Altogether, a total of 98 stroke patients with dysarthria participated in the study. INTERVENTIONS: Patients were randomly divided into two groups (the experimental group: basic articulation plus Liuzijue Qigong, 48 patients or the control group: basic articulation plus traditional breathing training, 50 patients). All therapies were conducted once a day, five times a week for three weeks. MAIN MEASURES: Primary outcome measure: speech breathing level of the modified Frenchay Dysarthria Assessment. Secondary outcome measures: the modified Frenchay Dysarthria Assessment, maximum phonation time, maximal counting ability, s, z, s/z ratio, and the loudness level. All outcome measures were assessed twice (at baseline and after three weeks). RESULTS: At three weeks, There were significant difference between the two groups in the change of speech breathing level (81% versus 66%, p = 0.011), the modified Frenchay Dysarthria Assessment (5.54 (4.68 to 6.40) versus 3.66 (2.92 to 4.40), p = 0.001), maximum phonation time (5.55 (4.92 to 6.18) versus 3.01 (2.31 to 3.71), p < 0.01), maximal counting ability (3.08 (2.45 to 3.71) versus 2.10 (1.53 to 2.67), p = 0.018), and s (3.08 (2.39 to 3.78) versus 1.87 (1.23 to 2.51), p = 0.004), while no significant differences were found in the change of z (3.08 (2.31 to 3.86) versus 2.10 (1.5 to 2.64), p = 0.08), s/z ratio (1.26 (0.96 to 1.55) versus 1.03 (0.97 to 1.09), p = 0.714), and the change of loudness level (69% versus 60%, p = 0.562). CONCLUSIONS: Liuzijue Qigong, combined with basic articulation training, could improve the respiratory control ability, as well as the comprehensive speech ability of stroke patients with dysarthria. TRIAL REGISTRATION: ChiCTR-INR-16010215.

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