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Afternoon aerobic and resistance exercise have limited impact on 24-h CGM outcomes in adults with type 1 diabetes: a secondary analysis [with consumer summary]
Brockman NK, Sigal RJ, Kenny GP, Riddell MC, Perkins BA, Yardley JE
Diabetes Research and Clinical Practice 2021 Jul;177:108874
clinical trial
4/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: No; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

AIMS: This study examined post-exercise glycemic variability in individuals with type 1 diabetes after acute bouts of resistance (RE) and aerobic exercise (AE) compared to a no-exercise day (CON). We hypothesized that exercise days would have greater glucose variability (standard deviation -- SD, coefficient of variation -- CV), and less time in range (TIR), compared to CON. METHODS: A secondary analysis was conducted on previously collected data. Twelve active participants with type 1 diabetes performed three testing sessions in random order with at least 48 h in between: AE (45-min treadmill run at 60%VO2max), RE (three sets of eight repetitions, seven weight-lifting exercises), and CON (45-min no-exercise control). Interstitial glucose levels were monitored by blinded continuous glucose monitoring (CGM). Glycemic variability was evaluated for 0 to 6 h, overnight (00:00 to 06:00) and 24 h after exercise. RESULTS: Mean CGM glucose, TIR, and time above/below range were similar among conditions (p > 0.05). Lower SD (0.8 (0.5 to 1.1), 1.4 (0.9 to 2.4) mmol/L, p = 0.009) and CV (11.4% (8.6 to 15.3), 23.4% (13.7 to 31.6), p = 0.007) were found overnight after AE versus CON. Otherwise, AE and RE had limited impact on post-exercise glycemia. CONCLUSIONS: Acute RE and AE bouts may have limited impact on post-exercise glycemic variability compared to rest in habitually active individuals with type 1 diabetes.
With permission from Excerpta Medica Inc.

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