BACKGROUND: Worldwide, breast cancer is the most common type of cancer. Among females, it's the main cause of cancer death. Chemotherapy-induced peripheral neuropathy (CIPN) is a prevalent serious side effect deriving from neurotoxic chemotherapeutic agents and a limiting factor in using them. The underlying nerve injury can affect proprioception and foot sensitivity causing impaired postural control. Sensory re-education is a therapeutic rehabilitation program that uses repeated sensory stimulation to recover functional sensibility in the affected area and learn adaptive functioning. PURPOSES: to study the effect of sensory re-education paradigm on postural stability in patient with CIPN. METHODOLOGY: Thirty CIPN female patients were randomly assigned in two equal groups. The control group (A) received a selected physical therapy program for 18 sessions. The study group (B) received the same physical therapy program in addition to a designed sensory re-education program for 18 sessions every other day. Pre-and post-treatment assessment were performed using Biodex balance system and Semmes-Weinstein monofilament. RESULTS: There was a statistically significant improvement in feet sensitivity and postural stability parameters in both groups in favor of the study group. CONCLUSIONS: The designed sensory re-education paradigm has improved postural stability and foot sensation significantly in survived breast-cancer females with CIPN.

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