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Effect of hip CPM on gross motor function and development of the hip joint: a single-center randomized controlled study on spastic cerebral palsy children with hip dysplasia
Wang L, Zhang N, Fang L, Cui Z, Niu H, Lv F, Hu D, Wu D
Frontiers in Pediatrics 2023 May 9;11(1090919):Epub
clinical trial
3/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: No; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

OBJECTIVE: To investigate the effectiveness of hip continuous passive motion (hCPM) on hip development at skeletal maturity and gross motor function for spastic cerebral palsy children with hip dysplasia. METHODS: Prospective case-control research of hCPM with goal-directed training versus merely goal-directed training. On the basis of goal-directed training, the hCPM group used the hip joint CPM instrument (the external fixator was connected to the power device to make the hip joint carry out continuous passive movement) for 40 to 60 min, twice a day, and five times a week, and received continuous training for 8 weeks simultaneously. The control group received only goal-directed training for 8 weeks. Functional outcomes pertaining to the affected hip joints were assessed via gross motor function measure (GMFM), migration percentage (MP), acetabular index (AI), and Harris hip functional score (HHS) at the time of enrollment and the end of the intervention. RESULTS: The case-control research included 65 participants (mean age 46.20 months, SD 17.09 months; Gross Motor Function Grading System level III = 41, IV = 24) who were randomly selected to either the hCPM (n = 45) or the control group (n = 20). No differences were found in baseline (acquisition phase) GMFM, MP, AI, or HHS (t = -1.720, p = 0.090; t* = 1.836, p* = 0.071; t# = -1.517, p# = 0.139; t* = -1.310, p* = 0.195; t# = -1.084, p# = 0.097; t = -1.041, p = 0.301). At the 8-week follow-up, GMFM, MP, AI, and HHS significantly improved over baseline in the hCPM group (hCPM group t = 18.59, 20.172*, 40.291#, 16.820*, 32.900#, 28.081; p < 0.001). Between-group differences at 8-week follow-up times points favored the hCPM group for GMFM (t = -2.637, p = 0.011), MP (t* = 2.615, p* = 0.014; t# = 3.000, p# = 0.006), AI (t* = 2.055, p* = 0.044; t# = 2.223, p# = 0.030), HHS (t = -4.685, p < 0.001) (* left side; # right side). CONCLUSIONS: Spastic cerebral palsy children with hip dysplasia achieved meaningful functional improvement after 8 weeks of goal-directed training with hCPM therapy.

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