AIMS: To review the content and efficacy of physical activity (PA) for cancer-related fatigue (CRF) among colorectal cancer survivors. DESIGN: Systematic review. METHODS: A comprehensive search for randomized controlled trials from inception to April 1, 2022, of the following database was performed: EMBASE, PubMed, Web of Science, Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang Data and China Biology Medicine (CBM). RevMan5.4 software was used for performing meta-analysis. RESULTS: A total of eight qualified randomized controlled trials that included 542 survivors were included. PA interventions significantly reduced the CRF (SMD -0.46, 95% CI -0.76 to -0.15, Z 2.67, p = 0.003), Subgroup analysis showed that fatigue was significantly improved when the length of interventions was at least 6 months and the weekly duration of PA was less than 150 min/week (SMD -0.54, 95% CI -0.81 to -0.27, Z 3.87 and p = 0.0001, SMD -0.67, 95% CI -1.15 to -0.19, Z 2.74 and p = 0.006), PA intervention with the length of < 6 months and the volume of >= 150 min/week did not reduce fatigue (p > 0.05).

Full text (sometimes free) may be available at these link(s):      help

• PubMed Central
• DOI
• PubMed
• PDF locator
• publisher