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| Neonatal and home-based PT improves neurodevelopmental outcomes of preterm infants -- a randomized clinical trial [with consumer summary] |
| Khurana S, Lewis LE, Russell DM, Dusing SC, Krishna Rao B |
| Pediatric Physical Therapy 2025 Apr;37(2):218-230 |
| clinical trial |
| 6/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: Yes; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
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PURPOSE: Investigate the effect of structured neonatal physical therapy program (SNP) on neurodevelopmental outcomes of moderate and late preterm (MLP) infants. METHODS: Sixty MLP infants were randomly allocated to usual care (UC) or SNP. A previous publication reported the effect of neonatal component of SNP at hospital discharge. This paper examined SNP's effect on motor, cognitive and language outcomes at 3 and 6 months using a 2-way mixed design ANOVA. RESULTS: Both groups were similar at baseline for motor scores. Infants receiving SNP significantly outperformed UC at all subsequent time points. At 3 and 6 months, SNP significantly outscored UC in cognitive and language outcomes. CONCLUSIONS: NP is effective in improving neurodevelopmental outcomes of MLP infants. However, caution is suggested in interpreting its effect on cognition and language as we lacked baseline scores to compare the longitudinal trajectory.
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