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Harnessing mirror neurons: improving balance and quality of life after a stroke
Sharma P, Ali Z, George SS
Cureus 2025 Mar;17(3):e81290
clinical trial
This trial has not yet been rated.

BACKGROUND: Action observation engages brain motor networks, and action imitation helps neurological and musculoskeletal problem patients improve motor learning and functional recovery. In this study, we focused on identifying the impact of action observation training (AOT) on balance and quality of life (QOL) in hemiparetic stroke patients. METHOD: A quasi-experimental study in Bengaluru (from December 2021 to July 2022) involved 60 hemiparetic patients randomly divided into two groups. Group A received 30 minutes of AOT alongside standard physiotherapy, while Group B received conventional therapy. Sessions focused on balance exercises, and outcomes were assessed using the Berg Balance Scale (BBS) and the Stroke-Specific Quality of Life (ss-QOL) scale. Statistical analyses, including paired and independent t-tests, highlighted significant differences, ensuring methodological rigor and ethical compliance. RESULTS: The findings show a significant difference in the pretest BBS scores between the experimental and control groups (p = 0.010), with the experimental group having a lower baseline. However, there was no significant difference in posttest BBS scores (p = 0.431). Both groups showed significant improvements in their BBS and ss-QOL scores (p < 0.05). The experimental group showed a larger improvement in BBS (p = 0.001), while ss-QOL improvements were not statistically significant (p = 0.732). CONCLUSION: The study concluded that the experimental and control groups demonstrated significant improvements in balance and QOL after the intervention, with the experimental group showing significantly larger improvements in balance, compared to control group.

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