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An effective exercise-based intervention for improving mental health and quality of live measures: a randomized controlled trial
Atlantis E, Chow C, Kirby A, Singh MF
Preventive Medicine 2004 Aug;39(2):424-434
clinical trial
4/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

OBJECTIVES: This study investigates the effectiveness of 24-week aerobic and weight-training exercise plus behavior modification for mental health and quality of life (QOL) outcomes. METHODS: Mental health and QOL data was collected using the Depression Anxiety and Stress Scales and SF-36 Health Status Survey, respectively. Employees from a single work-site were randomized into either treatment or wait-list control groups. RESULTS: Mental Health (p = 0.005), Vitality (p < 0.001), General Health (p = 0.009), Bodily Pain (p = 0.005), Physical Functioning (p = 0.004), Depression (p = 0.048), and Stress (p = 0.036) scales significantly improved for the treatment group compared to wait-list controls after 24 weeks. CONCLUSIONS: Multimodal exercise is as effective as other single-modality exercise treatments for depressive symptoms and, in contrast to other studies, does improve stress symptoms and QOL outcomes.
Copyright by Academic Press.

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