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Effect of an electric stimulation facilitation program on quadriceps motor unit recruitment after stroke
Newsam CJ, Baker LL
Archives of Physical Medicine and Rehabilitation 2004 Dec;85(12):2040-2045
clinical trial
4/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: No; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

To compare maximum voluntary isometric torque (MVIT) and motor unit recruitment of the quadriceps after an electric stimulation facilitation program in persons affected by cerebrovascular accident (CVA). Three-week, randomized controlled trial with an electric stimulation facilitation program added to standard care. Inpatient rehabilitation center. Twenty patients receiving rehabilitation for first-time CVA (51.8 +/- 15.2y; days post-CVA, 38.4 +/- 40.0d). Patients were randomly assigned to study and control groups. All patients received standard physical therapy (PT) care. In addition, the study group received an electric stimulation facilitation program during weight-bearing and ambulatory activities of the PT program. MVIT and motor unit recruitment measured by interpolated twitch testing. A 2x4 repeated-measures analysis of variance was performed on measurements at 4 intervals: pretest, 1 week, 2 weeks, and 3 weeks. MVIT increased by 77% in patients receiving electric stimulation, compared with a 31% increase for the control group. There was a significant effect for assessment time only. Motor unit recruitment increased from 35% to 53% for the study group, whereas the control group recorded no change in recruitment ability. A significant interaction was recorded, indicating improved motor unit recruitment for the study group. A brief and dynamic electric stimulation facilitation program significantly improved motor unit recruitment in persons after CVA.

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