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(Effect of pressed acupuncture at baihui acupoint on thromboxane A2 and prostacyclin in treating vertebral artery type of cervical spondylosis) [Chinese - simplified characters] |
Zhuang L-X, Zhu F-P |
Zhongguo Linchuang Kangfu [Chinese Journal of Clinical Rehabilitation] 2004 Oct 25;8(30):6672-6673 |
clinical trial |
6/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: Yes; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
AIM: To explore the curative effect of pressed acupuncture mainly at the baihui acupoint on vertebral artery type of cervical spondylosis (CSA). METHODS: Totally 34 CSA patients, who were treated in the Guangdong University of Traditional Chinese Medicine, were randomly divided into two groups: treatment group (n = 17) and control group (n = 17). All the patients were treated with local electroacupuncture, and besides, those in the treatment group received pressed acupuncture at the baihui acupoint. The clinical curative effects were observed, the changes of contents of plasma thromboxane B2 (TXB2) and 6-keto-prostaglandin 1 alpha (6-keto-PGF1a) and the ratio of them were determined before and after treatment in both groups. RESULTS: The number of cases with cure, significant effect, improvement and without effect was 9, 6, 2 and 0 respectively in the treatment group, but 4, 4, 7 and 2 in the control group respectively, and the curative effect in the treatment group was obviously better than that in the control group (Chi2 = 6.58, p = 0.025). The TXB2 and 6-keto-PGF1a contents in the treatment group before treatment were 442.96 +/- 164.11 and 157.01 +/- 75.43 ng/L, after treatment were 144.22 +/- 127.81 and 368.85 +/- 117.09 ng/L, while those in the control group before treatment were 383.25 +/- 210.75 and 156.39 +/- 84.15, after treatment were 198.72 +/- 41.65 and 258.78 +/- 85.25 ng/L, there were significant differences before and after treatment in both groups (t = 5.92, 6.27, 3.0, 3.52, p < 0.01). The content of 6-keto-PGF1a after treatment in the treatment group was significantly different from that in the control group (t = 3.13, p < 0.01). CONCLUSION: Pressed acupuncture mainly at the baihui acupoint can effectively ameliorate the clinical symptoms of CSA patients, so as to diastole the vascular pressure.
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