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The use of graduated compression stockings in the prevention of postoperative deep vein thrombosis
Allan A, Williams JT, Bolton JP, le Quesne LP
The British Journal of Surgery 1983 Mar;70(3):172-174
clinical trial
5/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: No. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

The efficacy of graduated compression stockings in the prevention of postoperative deep vein thrombosis was studied in a randomized, prospective, controlled trial of 200 patients, aged 40 years and over, undergoing abdominal surgery (100 for benign disease, 100 for malignant conditions). Deep vein thrombosis was diagnosed by the 125I-fibrinogen test. The incidence of deep vein thrombosis was 35.9% in the control group (103 patients) and 15.5% in the stockinged group (97 patients) (p < 0.025). In the patients with benign disease, deep vein thrombosis developed in 24.5% of the control limbs and 6.1% of stockinged limbs (p < 0.005); in patients with malignant disease the similar figures were 27.9 and 11.5% (p < 0.05). Increasing age did not alter the efficacy of the stockings. It is concluded that graduated compression stockings provide a safe and effective method of prophylaxis against deep vein thrombosis.

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