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| Immediate effects of speed-dependent treadmill training on gait parameters in early Parkinson's disease |
| Pohl M, Rockstroh G, Ruckriem S, Mrass G, Mehrholz J |
| Archives of Physical Medicine and Rehabilitation 2003 Dec;84(12):1760-1766 |
| clinical trial |
| 5/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
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OBJECTIVE: To compare the immediate effects of different training interventions on gait parameters in patients with early Parkinson's disease (PD). DESIGN: Randomized, multiple intervention crossover pilot study. SETTING: A rehabilitation center for adult persons with neurologic disorders. PARTICIPANTS: Seventeen patients with early PD (Hoehn and Yahr stages I through III) and gait disturbances. INTERVENTION: Patients were randomly assigned to varying sequences of the following interventions over 4 consecutive days: structured speed-dependent treadmill training (STT), limited progressive treadmill training (LTT), conventional gait training (CGT), and a control intervention. MAIN OUTCOME MEASURES: Basic gait parameters (overground walking speed and stride length at self-adapted speeds) and parameters of gait analysis based on vertical ground reaction forces. RESULTS: STT and LTT improved all basic gait parameters and the double stance duration compared with preintervention values (p < 0.05). No changes were found after CGT and the control intervention (p < 0.05). Significantly higher gains were observed in all basic gait parameters after STT and LTT when compared with CGT and the control intervention (p < 0.05). Additionally, a greater reduction of double stance duration was found after STT than after the control intervention (p < 0.001). No significant differences in gains were observed between STT and LTT, or between CGT and the control intervention, in all gait parameters. CONCLUSION: The main disturbances of gait in PD, namely, speed and stride length, can be improved through a single intervention of STT or LTT, but not through CGT and the control intervention.
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