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The effects of physical training on blood lipid profiles in adolescents with insulin-dependent diabetes mellitus
Campaigne BN, Landt KW, Mellies MJ, James FW, Glueck CJ, Sperling MA
The Physician and Sportsmedicine 1985;13:83-89
clinical trial
5/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

Fourteen adolescents (eight females and six males) with insulin-dependent diabetes mellitus (IDDM) participated in a 12-week exercise program consisting of three 45-minute sessions per week. Exercise consisted of calisthenic warm-up and stretching (ten minutes), aerobic movement to music (25 minutes at 80% VO2max), and cool-down (ten minutes). The purpose was to determine whether and to what degree such training would bring about changes in blood lipid and lipoprotein profiles in such patients. The authors found a significant decrease in low-density lipoprotein cholesterol concomitant to an increase in VO2max with no change in glycemic control. These findings support the beneficial effects of regular exercise for individuals with IDDM.
Abstract reprinted with permission from The McGraw-Hill Companies. All rights reserved.

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