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| Effect of endurance training on blood pressure at rest, during exercise and during 24 hours in sedentary men |
| van Hoof R, Hespel P, Fagard R, Lijnen P, Staessen J, Amery A |
| The American Journal of Cardiology 1989 Apr 15;63(13):945-949 |
| clinical trial |
| 5/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
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The effect of 4 months of physical training on resting, exercise and 24-hour blood pressure (BP) was studied using a randomized crossover design in 26 healthy, sedentary men, with an average age of 39 +/- 10 (standard deviation) years. Peak oxygen uptake increased by 14% (p < 0.001) and the physical working capacity at a heart rate of 130 beats/min by 25% (p < 0.001). The heart rate was reduced by 7 beats/min at night (p < 0.01) and by 6 beats/min during the day (p < 0.001). Training-induced changes of BP varied according to measuring conditions. A decrease in BP at rest while sitting in the morning in the laboratory was significant for diastolic (-5 mmHg, p < 0.01) but not for systolic BP. During exercise, systolic BP was significantly lower after training, when measured at the same submaximal workloads. However, when workload was expressed as a percentage of peak oxygen uptake, systolic BP was not different before and after training. When measured during 24 hours, the training-induced change in BP was not significant at night either for systolic or diastolic BP. During the day the decrease in diastolic BP was significant (-5 mmHg, p < 0.001), but the change in systolic BP was not.
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