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| Treatment of surgical patients with postoperative purulent wounds by continuous microwave -- a new effective physical method |
| Korpan NN, Saradeth T, Resch KL |
| European Journal of Physical Medicine and Rehabilitation 1995;5(1):17-21 |
| clinical trial |
| 6/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: Yes; Blind therapists: Yes; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed* |
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BACKGROUND: As has been demonstrated in animal experiments, reparative processes are stimulated, and wound healing is enhanced by continuous microwave (CM). The aim of this study was to test the curative effects of this new physical method on the course of postoperative purulent and inflammatory processes in patients after abdominal surgical intervention. METHODS: In this double blind, controlled study, 60 males and 81 females (age 50.6 +/- 15.1 years) with postoperative septic wounds were randomized into 2 groups: 71 patients were treated by local, continuous microwave (group A), the other 70 cases received a placebo treatment with an identical, though defective device (group B, controls). The criteria of wound healing, as well as clinical, microbiological, hematological and immunological parameters were evaluated in both groups, RESULTS: Data analysis of the clinical and laboratory parameters comparing groups A and B showed that the curative effects were stronger in group A. Pain reduction was significantly accelerated in the postoperative wound area in group A. Criteria of wound healing demonstrated significantly better results in group A (treated with CM) than in the control group B: wound clearance was significantly accelerated (5.6 +/- 0.6 versus 10.2 +/- 0.5 days); similarly, the initial epithelization was significantly enhanced (7.0 +/- 0.4 versus 12.8 +/- 0.6 days); granulation appeared after 4.9 +/- 0.2 in group A versus 8.7 +/- 0.4 days of postoperative treatment in group B. The daily decrease of wound surface area was significantly higher in group A than in group B (7.1% versus 3.2%). CONCLUSIONS: The findings of this double blind, controlled, clinical trial suggest that low-intensity continuous microwave is effective in the postoperative treatment of purulent wounds of patients who underwent abdominal surgery. It may be promising to clarify the underlying mechanisms in future clinical trials and to optimize the curative effects of this new physical method.
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