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Fenbufen in the treatment of over-use injuries in long-distance runners
Noble C
Suid-Afrikaanse Tydskrif vir Geneeskunde [South African Medical Journal] 1981 Sep 5;60(10):387-388
clinical trial
3/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: No; Baseline comparability: No; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: No; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

A random-selection trial comparing fenbufen (Cinopal; Lederle) and reduction in training activity to reduction in training activity alone in over-use injuries in long-distance runners is described. Fenbufen and reduction of training activity together were found to be significantly superior to reduction of training activity alone and improved the signs and symptoms of over-use injuries in long-distance runners. Most of these injuries were of soft tissues, and in these cases it was found that fenbufen had a significant anti-inflammatory effect.

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