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Does exercise give an additional effect in weight reduction regimens?
van Dale D, Saris WH, Schoffelen PF, ten Hoor F
International Journal of Obesity 1987;11(4):367-375
clinical trial
4/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

The effects of dieting and exercise on RMR, body composition and maximal aerobic power were studied in 12 obese women. The subjects were paired on the basis of their body mass index and divided into a diet (D) and a diet+exercise group (DE). The treatment consisted of a 5-week period with a low-energy formula diet of 2.9 MJ and an 8-week period with a mixed diet of 1.7 MJ supplemented with 1.8 MJ normal foodstuffs. DE trained 4 h per week at 50 to 60% of their maximal aerobic power with aerobics and fitness exercises. Body composition was determined by hydrostatic weighing and RMR was measured from 03.00 to 06.00 hours in a respiration chamber. Maximal aerobic power was measured on a continuously braked ergometer. The measurements were done at week 0, after 4 weeks (week 5), and after 12 weeks (week 13). Weight loss after 4 weeks was 8.2 kg (DE) and 7.9 kg (D) and after 12 weeks 13.2 kg (DE) and 12.2 kg (D). There were no significant differences between the groups. Fat loss was also not statistically different between DE (6.7 and 10.9 kg) and D (6.0 and 9.4 kg). Both groups showed a significant decrease in RMR per kilogram FFM after 12 weeks (DE 18.2% and D 26.5%). There was also a significant decrease in RMR for D (19.9%) after 4 weeks but not for DE (12.2%).

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