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Cyclic sequential compression of the lower limb in prevention of deep venous thrombosis
Hartman JT, Pugh JL, Smith RD, Robertson WW Jr, Yost RP, Janssen HF
Journal of Bone and Joint Surgery -- American Volume 1982 Sep;64(7):1059-1062
clinical trial
2/10 [Eligibility criteria: Yes; Random allocation: No; Concealed allocation: No; Baseline comparability: No; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: No. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

Patients undergoing operations on the hip for either replacement or fracture were chosen for this study. Fifty-two subjects received cyclic sequential compression as well as elevation of the lower limb while another fifty-two patients were treated with only elevation of the lower limb. No other method of prophylaxis for deep venous thrombosis was employed during the study period. Support stockings were used after removal of the compression device. Doppler ultrasound, phleborheography, and, when possible, radioiodinated fibrinogen scanning were used for identification and location of thrombi. A deep-vein thrombosis developed in ten patients (19%) in the control group and in only one patient (2%) in the group that was treated with compression. This difference is statistically significant (p < 0.05).

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