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Hemodynamic effects of physical training in established arterial hypertension
de Plaen JF, Detry JM
Acta Cardiologica 1980;35(3):179-188
clinical trial
2/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: No; Baseline comparability: No; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: No; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

Six patients with established arterial hypertension have been studied before and after a three months period of regular intense physical training. After training the maximal oxygen uptake was 9.6% higher (p < 0.02) and the heart rate was lower at rest (-8 beats/min; NS) and during submaximal exercise (-12 beats/min; p < 0.001). This bradycardia was attended by a slight decrease in cardiac output and an increase in the arterio-mixed venous oxygen difference; the blood pressure was unchanged and, accordingly, the peripheral resistance were slightly increased after training (+17%, p < 0.005 at rest and +6.5% NS during exercise). We concluded that physical training has no specific hypotensive effect in patients with established arterial hypertension; in these patients the changes induced by training are very similar to those observed in normal subjects or in patients with coronary artery disease.

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