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A controlled trial of assisted ventilation using an oro-nasal mask
Llewellyn MA, Tilak KS, Swyer PR
Archives of Disease in Childhood 1970 Aug;45(242):453-459
clinical trial
5/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: Yes; Baseline comparability: No; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

A contolled study was performed to assess the effect of early assisted ventilation using a tight fitting face mask. Early mask ventilation reduced the number of infants requiring intubation, but did not significantly alter the infant survival rate. Complications were seen in infants during both mask ventilation and ventilation with a naso-tracheal tube. Persistent radiological changes were seen in 5 of 9 infants who survived after ventilation for more than 5 days.
Reproduced with permission from the BMJ Publishing Group.

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