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(Effect of the treatment of Chinese medicine heated adhesion together with manipulation and traction on the hemorheology in patients with prolapse of lumbar intervertebral disc) [Chinese - simplified characters]
Zhou D-Q, Zhou S-Q, Wei L-H, Zhou Q, Wu Y-Q
Zhongguo Linchuang Kangfu [Chinese Journal of Clinical Rehabilitation] 2006 Jan 20;10(3):18-20
clinical trial
5/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: Yes; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

AIM: To observe the effects of the treatment of Chinese medicine heated adhesion together with manipulation and traction on the hemorheology in patients with prolapse of lumbar intervertebral disc (PLID). METHODS: (1) Totally 120 patients (76 males and 44 females) with PILD who were cured in the Department of Orthopedics of the Fourth Hospital of Guangxi Medical College from November 2003 to May 2005 were randomly divided into experimental group and control group with 60 patients in each group. They were told the purpose of experiment and consent. Normal value in hemorheolegy could be got from Huaxi Medical College who used the automatic cleaning rotation viscosity meter to determine more than 10,000 persons. (2) Controls group: lumbar intervertebral disc hernias was treated only by the automatic traction bed, and weight accounted for 25% to 100% of body's mass, 30 minutes one time, one time per day, six times for a period. Experimental group: patients received the same therapy as control group, while combining that with Chinese medicine heated adhesion and manipulation (prescription as follows: shengchuanwu, shengcaowu, huajiao and yangjinhua with 20 g of each; shenjincao, tougucao, dangkui and honghua with 30 g of each; yanhusuo, chuanxiong, tubiewang, ruxiang, moyao, weilingxian, liujinu, mahuang, and xixin with 15 g of each; buguzhi and gusuibu with 10 g of each. the hot cloth bag with the above mentioned medicine was placed on patient's lumbar spine bottom, and the cool cloth bag with another one hot was replaced, 30 minutes one time, one time per day, six times for a period. The time of treatment was about 40 minutes, six days for a period. (3) The tallcut viscosity and the lowcut viscosity of whole blood, plasma viscosity, aggregation exponent, rigidity exponent of patients in this group were measured by the viscosity meter before and after treatment. Wintrobe tube was used to determined blood corpuscle and Clauss method was used to determine fibrinogen. (4) Sample average and count data were handle by t test and Chi2 test, respectively. RESULTS: Totally 120 PILD patients entered the final analysis. (1) Before treatment, the tallcut viscosity and the lowcut viscosity of whole blood, plasma viscosity, aggregation exponent, rigidity exponent and fibrinogen of patients in the two groups were obvious higher than those of normal value (p < 0.05). As compared with normal value, the differences of pressure of erythrocyte were not significant (p > 0.05). The differences in the hemorheology items were not very significant between the experimental and the control before treatment (p > 0.05). (2) After receiving treatment, only lowcut rate of blood viscosity and fibrinogen in the control group were obvious lower than those before treatment (p < 0.05); however, other values were not significantly different (p > 0.05). Values of tallcut viscosity and the lowcut viscosity of whole blood, plasma viscosity, fibrinogen and aggregation exponent in the experimental group were significantly lower than those before treatment (p < 0.05), but values of pressure of erythrocyte and rigidity exponent were not significantly different as compared those before treatment (p > 0.05). CONCLUSION: Traditional Chinese medicine heated adhesion in combination with manipulation and traction has some adjusted action to hemorheology, blood motion and microcirculation in patients with PILD, and the effective is much better than only by traction.

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