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Comparison of stochastic versus conventional transcutaneous electrical stimulation for pain modulation in patients with electromyographically documented radiculopathy
Bloodworth DM, Nguyen BN, Garver W, Moss F, Pedroza C, Tran T, Chiou-Tan FY
American Journal of Physical Medicine & Rehabilitation 2004 Aug;83(8):584-591
clinical trial
4/10 [Eligibility criteria: No; Random allocation: Yes; Concealed allocation: No; Baseline comparability: No; Blind subjects: Yes; Blind therapists: No; Blind assessors: Yes; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: No. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

OBJECTIVE: To determine if a transcutaneous electrical stimulation (TENS) unit modified to deliver electrical impulses at random (R) or stochastic frequency, called TENS-R, provided better pain relief than conventional TENS. DESIGN: A prospective, randomized, double-blinded, placebo-controlled study at an urban teaching hospital. A total of 13 adult subjects with radiculopathy on electromyogram and chronic radicular pain rated pain before and after walking 100 feet with proximal (axial) placement of TENS leads with randomized settings on conventional TENS, placebo, or TENS-R and, subsequently, with distal (limb) placement of TENS leads with randomized settings, all on the same day. The pain measures used were the McGill Pain Questionnaire, parts 1 and 2, and the visual analog scale. The functional measure was speed of walking. RESULTS: Four men and seven women completed the study pain scores, measured by McGill Pain Questionnaire part 2, significantly improved when the patient used TENS-R versus conventional TENS (p = 0.006, analysis of variance). Placement of TENS electrodes on the back significantly decreased pain compared with lead placement on the legs for McGill Pain Questionnaire part 1 (p = 0.007), McGill Pain Questionnaire part 2 (p = 0.042), and the visual analog scale (p = 0.026) measures. CONCLUSIONS: Qualitative pain scores significantly improved when the patient used TENS-R versus conventional TENS. Lead placement of any TENS modality over the back versus over the leg improved all pain scores.

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