Use the Back button in your browser to see the other results of your search or to select another record.

Detailed Search Results

Severe versus moderate energy restriction with and without exercise in the treatment of obesity: efficiency of weight loss
Sweeney ME, Hill JO, Heller PA, Baney R, DiGirolamo M
The American Journal of Clinical Nutrition 1993 Feb;57(2):127-134
clinical trial
4/10 [Eligibility criteria: Yes; Random allocation: Yes; Concealed allocation: No; Baseline comparability: Yes; Blind subjects: No; Blind therapists: No; Blind assessors: No; Adequate follow-up: No; Intention-to-treat analysis: No; Between-group comparisons: Yes; Point estimates and variability: Yes. Note: Eligibility criteria item does not contribute to total score] *This score has been confirmed*

Thirty obese women were randomly assigned to either 40% (severe energy restriction (SER)) or 70% (moderate energy restriction (MER)) of their maintenance energy requirements and to no exercise, aerobic exercise (walking), or aerobic exercise plus circuit weight training. Body composition by hydrostatic weighing and energy expenditure by indirect calorimetry were measured at 0, 3, and 6 mo. In addition, we developed a deficit-efficiency factor (DEF), calculated as body energy loss/dietary energy deficit, to attempt to quantify the effectiveness of the weight-reduction interventions. Subjects in the SER group lost more weight (mean +/- SE: 15.1 +/- 1.4 versus 10.8 +/- 1.0 kg), fat (11.7 +/- 1.1 versus 8.3 +/- 0.6 kg), and fat-free mass (2.8 +/- 0.3 versus 1.8 +/- 0.3 kg) than the MER group (p <= 0.05). However, the overall DEF was greatest in the MER group (0.80 +/- 0.07) compared with the SER group (0.52 +/- 0.05; p <= 0.01). Exercise had no significant effect. This study demonstrates that MER may offer an advantage over SER because it produces a greater energy loss relative to energy deficit.
Copyright by the American Society for Clinical Nutrition.

Full text (sometimes free) may be available at these link(s):      help